'Dose-response' effect - Tradução em português

Looking at the graph in the paper, which is split by both age and gender, the confidence intervals (a measure of accuracy of the findings) are quite wide. This is particularly true for the women. In fact, from their graph it can be seen that, in the highest coffee consumers, there may actually be no difference between the age groups or genders, as the confidence intervals all cross each other.
Another slightly unusual aspect of the findings is that there's no 'dose-response' effect. If there was something in coffee that increased your risk of death, you would expect that a little bit of coffee would increase your risk a bit, and more would be more harmful still. However, their results and conclusions suggest that it's only for extreme levels of coffee consumption that a risk is seen.

Por favor, traduzir o que estiver destacado. Obrigado.