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Smog in China has been a huge problem in big cities like ["as" must introduce a verbal clause] Beijing, Shangai and many others. I grew up in Shangai and spent many years trying to heal my respiratory problems. I used to take many pills, but to not avail. When I got married, we moved into a small city and my health problem disappeared ["to despair" = to lose hope or go into a state of desperation].
Over the last years, the Chinese government has spent millions of dollars (in attempts) to change this situation in China. According to the World Health Organization, the air quality in China is below than normal / accepted levels.
I used to take many pills, but to no avail.