Withdrawn / Set in - Tradução em português

Pessoal, vocês poderiam me ajudar na tradução das duas palavras em negrito ?

These strengths may mask the severity of the many real deficits.9It is a common misconception that children with autism must be withdrawn; some are, but others are perfectly friendly. Real, and tragic, isolation sets in later if they do not develop the social and communication skills expected of older children.

Agradeço desde já.